About dopamine, reward prediction and addiction

“If you can’t predict where and when you’re going to get food, shelter, or sex in response to specific stimuli, you’re going to be a very hungry, chilly and undersexed organism.”

http://scientopia.org/blogs/scicurious/2011/06/29/repost-dopamine-and-reward-prediction-or-your-brain-on-rickroll/

and then..

“This seems nonsensical. If the drug no longer works to produce pleasure like it used to do, then why continue to take it? It may be because dopamine-active brain circuits are no longer accurately computing reward prediction errors. Not even close. The research suggests that an addict’s brain no longer registers negative responses to drugs as reward errors. Instead, all that remains is the reinforcing signals from the dopamine neurons: Get more drugs.”

http://addiction-dirkh.blogspot.pt/2012/01/reward-and-punish-say-hello-to.html

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